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Formation of urea inside the body takes place in

  By GK Planet Team      
Q. Formation of urea inside the body takes place in
  1. kidneys
  2. urinary bladder
  3. lungs
  4. liver
Answer: Liver

Formation of urea takes place in the liver of the body.

Liver


The liver is an organ only found in vertebrates which detoxifies various metabolites, synthesizes proteins and produces biochemicals necessary for digestion and growth.

The liver is responsible for the breakdown of insulin and other hormones. The liver breaks down bilirubin via glucuronidation, facilitating its excretion into bile. The liver is responsible for the breakdown and excretion of many waste products. It plays a key role in breaking down or modifying toxic substances (e.g., methylation) and most medicinal products in a process called drug metabolism. This sometimes results in toxication, when the metabolite is more toxic than its precursor. Preferably, the toxins are conjugated to avail excretion in bile or urine. The liver converts ammonia into urea as part of the urea cycle, and the urea is excreted in the urine.

The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.

A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 55-65% of the liver's mass.

Kidney


Kidneys are two organs in the abdomen of vertebrates that are shaped like beans. The prefix nephro- is also used in words to mean "kidneys". For example, a nephrologist is a doctor who studies kidneys.

The kidney makes hormones. The two most important ones that it makes are erythropoietin and renin.

The kidneys excrete a variety of waste products produced by metabolism into the urine. The microscopic structural and functional unit of the kidney is the nephron. It processes the blood supplied to it via filtration, reabsorption, secretion and excretion; the consequence of those processes is the production of urine. These include the nitrogenous wastes urea, from protein catabolism, and uric acid, from nucleic acid metabolism. The ability of mammals and some birds to concentrate wastes into a volume of urine much smaller than the volume of blood from which the wastes were extracted is dependent on an elaborate countercurrent multiplication mechanism. This requires several independent nephron characteristics to operate: a tight hairpin configuration of the tubules, water and ion permeability in the descending limb of the loop, water impermeability in the ascending loop, and active ion transport out of most of the ascending limb. In addition, passive countercurrent exchange by the vessels carrying the blood supply to the nephron is essential for enabling this function.
The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
Urea is produced in the liver and transported to the kidneys and finally excreted as a waste product in urine.
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Thanks for reading Formation of urea inside the body takes place in

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